Potassium Hydroxide → HCID 54288664, compound

HRID 2419571Notes

Reaction equation

HRID 2419571 reaction equation
[OH-].[K+].[CH2:3]([O:5][C:6]1[CH:14]=[CH:13][C:9]([CH2:10][C:11]#[N:12])=[CH:8][CH:7]=1)[CH3:4].[CH2:15]([O:21][C:22]1[CH:29]=[CH:28][C:25]([CH:26]=O)=[CH:24][CH:23]=1)[CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]>CO>[CH2:3]([O:5][C:6]1[CH:14]=[CH:13][C:9]([C:10](=[CH:26][C:25]2[CH:28]=[CH:29][C:22]([O:21][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])=[CH:23][CH:24]=2)[C:11]#[N:12])=[CH:8][CH:7]=1)[CH3:4]

Participants

5

Reactant 3

HCID 14797Potassium HydroxideHCID 79816p-(Hexyloxy)benzaldehydeHCID 5839052-(4-Ethoxyphenyl)acetonitrile

Product 1

HCID 54288664HCID 54288664, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2 g of KOH were dissolved in 30 ml of methanol whilst being heated. The solution was cooled down to room temperature, after which 3.3 g of p-ethoxybenzylcyanide and 4 g of p-hexyloxybenzaldehyde were added. The mixture was stirred and subsequently stored at room temperature for 1 hour and then at -25° C for 2 hours. The crystallisate was filtered off and subsequently recrystallized from methanol and petroleum ether (60-80). Melting point 53.5°-54° C. Transition point nematic-isotropic 80° C. In a similar way the following compounds were obtained:

Workup

  1. temperaturewhilst being heated
  2. waitat -25° C for 2 hours
  3. filtrationThe crystallisate was filtered off
  4. customsubsequently recrystallized from methanol and petroleum ether (60-80)
  5. customTransition point nematic-isotropic 80° C
  6. customIn a similar way the following compounds were obtained

Sources & evidence

ORD record
ord-d8b36055fcd04d91b9ac174956808cb6
Source dataset
uspto-grants-1978_08
Patent number
US04107189

Reaction notes

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