HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene → 3-(Dimethoxymethyl)hept-2-en-4-yne
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | 1,1-Dimethoxyhex-3-yn-2-one | HCID 20314017 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Catalyst | Phosphonium, ethyltriphenyl-, bromide (1:1) | HCID 73727 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | 3-(Dimethoxymethyl)hept-2-en-4-yne | HCID 71441464 | — |
Reaction Steps
Ethyltriphenylphosphonium bromide (24.8 g) is stirred with 100 ml benzene, and 40 ml (1.6 N) butyl lithium in hexane is added over about 1/2 hour with a water bath used to take up the slight heat of reaction. The mixture (bright orange) is stirred at room temperature for 0.75 hour, and 10.0 g of the 1,1-dimethoxy-3-hexyne-2-one is added dropwise in 1/2 hour.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04107217 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-ccc1b75422584322bb4a6dd5412e0f2f |
| Source note | uspto-grants-1978_08 |