HCID 12493309, compound → HCID 178420612, compound

HRID 2419668Notes

Reaction equation

HRID 2419668 reaction equation
CS[C:3]1[N:8]2[CH:9]=[N:10][CH:11]=[C:7]2[CH:6]=[N:5][N:4]=1.[NH2:12][C:13]1[CH:17]=[CH:16][NH:15][N:14]=1>C1(C)C=CC=CC=1>[NH:15]1[CH:16]=[CH:17][C:13]([NH:12][C:3]2[N:8]3[CH:9]=[N:10][CH:11]=[C:7]3[CH:6]=[N:5][N:4]=2)=[N:14]1

Participants

4

Reactant 2

HCID 12493309HCID 12493309, compoundHCID 178418806HCID 178418806, compound

Product 1

HCID 178420612HCID 178420612, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Conditions

Temperature
0 °C

Procedure

A mixture of 6.0 gm. of 4-(methylthio)-imidazo[1,5-d]-as-triazine, 4.15 gm. of 3-aminopyrazole and 150 ml. of toluene is refluxed for 26 hours. The mixture is evaporated and the residue is heated with a mixture of 150 ml. of ethanol and 40 ml. of dimethylformamide. The mixture is cooled to 0° C. and the desired product is collected as a solid, m.p. 271°-274° C.

Workup

  1. additionA mixture of 6.0 gm
  2. customThe mixture is evaporated
  3. temperaturethe residue is heated with a mixture of 150 ml
  4. customthe desired product is collected as a solid, m.p. 271°-274° C.

Sources & evidence

ORD record
ord-8672add46bf64596a4f2e23d28ce081a
Source dataset
uspto-grants-1978_08
Patent number
US04107308

Reaction notes

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