Water → 4,5-Dimethyl-2-n-propyl-2-imidazoline-4,5-diol hydrochloride

HRID 2419692Notes

Reaction equation

HRID 2419692 reaction equation
[ClH:1].[C:2]([NH2:7])(=[NH:6])[CH2:3][CH2:4][CH3:5].[OH-:8].[Na+].[OH2:10]>>[ClH:1].[CH3:2][C:3]1([OH:10])[C:4]([CH3:5])([OH:8])[NH:7][C:2]([CH2:3][CH2:4][CH3:5])=[N:6]1

Participants

4

Reactant 3

HCID 962WaterHCID 14798Sodium HydroxideHCID 12828983Butanimidamide hydrochloride

Product 1

HCID 124932794,5-Dimethyl-2-n-propyl-2-imidazoline-4,5-diol hydrochloride

Procedure

A 112.7 gm. portion of butyramidine hydrochloride is dissolved in 200 ml. of water. A 107 gm. portion of freshly distilled diacetyl is added and the mixture is stirred. The pH is adjusted to 6.5-7.0 with 2N NaOH and the solution is chilled. The desired product is collected as a solid, m.p. 104°-107° C.

Workup

  1. additionportion of freshly distilled diacetyl is added
  2. temperaturethe solution is chilled
  3. customThe desired product is collected as a solid, m.p. 104°-107° C.

Sources & evidence

ORD record
ord-286c3be6593f4b7b90a5e3753231ee02
Source dataset
uspto-grants-1978_08
Patent number
US04107307

Reaction notes

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