Methyl carbazate → HCID 136388419, compound

HRID 2419752Notes

Reaction equation

HRID 2419752 reaction equation
[CH3:1][C:2]1[NH:6][C:5]([C:7]2[CH:8]=[C:9]([CH3:13])[CH:10]=[CH:11][CH:12]=2)=[N:4][C:3]=1[CH:14]=O.[C:16]([O:20][CH3:21])(=[O:19])[NH:17][NH2:18]>C(O)(=O)C.C(Cl)Cl>[CH3:1][C:2]1[NH:6][C:5]([C:7]2[CH:8]=[C:9]([CH3:13])[CH:10]=[CH:11][CH:12]=2)=[N:4][C:3]=1[CH:14]=[N:18][NH:17][C:16]([O:20][CH3:21])=[O:19]

Participants

5

Reactant 2

HCID 80519Methyl carbazateHCID 224119984-Methyl-2-(3-methylphenyl)-1H-imidazole-5-carboxaldehyde

Product 1

HCID 136388419HCID 136388419, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidCatalystHCID 6344DichloromethaneSolvent

Procedure

A mixture of 5-methyl-2-m-tolyl-4-imidazolecarboxaldehyde (6.9 g, 0.034 mole), methyl carbazate (3.1 g, 0.034 mole). methylene chloride (70 ml) and acetic acid (1 drop) is refluxed for 1 hour. The precipitated white solid is collected by filtration to yield 7.1 g (0.026 mole), mp. 162°-164° c.

Workup

  1. filtrationThe precipitated white solid is collected by filtration
  2. customto yield 7.1 g (0.026 mole), mp. 162°-164° c

Sources & evidence

ORD record
ord-ea6d4553a1fd464e9361a0a22a543780
Source dataset
uspto-grants-1978_08
Patent number
US04107307

Reaction notes

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