Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Phenol | HCID 996 | — |
| Reactant | Phosphoric Acid | HCID 1004 | — |
| Reactant | Isoprene | HCID 6557 | — |
| Catalyst | Phenothiazine | HCID 7108 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | 3,3-Dimethylindan-5-ol | HCID 78660 | 33.1% |
Reaction Steps
322 g of isoprene, stabilized with 1 g of phenothiazine, were added dropwise over the course of 8 hours to a solution of 403 g of phenol, 50 g of 85% strength phosphoric acid and 9 ml of water in 2.14 liters of xylene at 110° C. To complete the reaction, the mixture was stirred overnight at 110° C. The acid phase was separated off and the organic phase was washed until neutral. Fractional distillation gave 230 g of 3,3-dimethyl-5-hydroxy-indane, boiling point 132°-134° C/10 mm Hg; melting point 84.5° -86.5° C. ##STR30##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04107324 |
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| Source dataset | uspto-grants-1978_08 |
|---|
| ORD ID | ord-1951b4c026074b19820d15e0600722e6 |
|---|
| Source note | uspto-grants-1978_08 |
|---|
