Sulfuric Acid → [3,4'-Bipyridin]-6(1H)-one

HRID 2419774Notes

Reaction equation

HRID 2419774 reaction equation
[O:1]=[C:2]1[NH:9][CH:8]=[C:7]([C:10]2[CH:15]=[CH:14][N:13]=[CH:12][CH:11]=2)[CH:6]=[C:3]1C#N.O=C1NC=C(C2C=CN=CC=2)C=C1C(O)=O.S(=O)(=O)(O)O>>[N:13]1[CH:14]=[CH:15][C:10]([C:7]2[CH:6]=[CH:3][C:2](=[O:1])[NH:9][CH:8]=2)=[CH:11][CH:12]=1

Participants

4

Reactant 3

HCID 1118Sulfuric AcidHCID 1319896-Oxo-1,6-dihydro-3,4'-bipyridine-5-carbonitrileHCID 128733622-Oxo-5-(pyridin-4-yl)-1,2-dihydropyridine-3-carboxylic acid

Product 1

HCID 13289548[3,4'-Bipyridin]-6(1H)-one

Procedure

The process according to claim 12 which comprises reacting 1,2-dihydro-2-oxo-5-(4-pyridinyl)-nicotinonitrile or 1,2-dihydro-2-oxo-5-(4-pyridinyl)-nicotinic acid with aqueous sulfuric acid to produce 5-(4-pyridinyl)-2(1H)-pyridinone.

Sources & evidence

ORD record
ord-eb0ed5c215854b19840032273408ac48
Source dataset
uspto-grants-1978_08
Patent number
US04107315

Reaction notes

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