Acetic Acid → HCID 178476576, compound

HRID 2419780Notes

Reaction equation

HRID 2419780 reaction equation
[CH2:1]([NH:8][C:9]([NH:11][N:12]=[CH:13][C:14]1[C:19]([Cl:20])=[CH:18][CH:17]=[CH:16][C:15]=1[Cl:21])=[NH:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:22]([OH:25])(=[O:24])[CH3:23]>C(O)C>[C:22]([OH:25])(=[O:24])[CH3:23].[C:22]([OH:25])(=[O:24])[CH3:23].[CH2:1]([NH:8][C:9]([NH:11][N:12]=[CH:13][C:14]1[C:15]([Cl:21])=[CH:16][CH:17]=[CH:18][C:19]=1[Cl:20])=[NH:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 176Acetic AcidHCID 178512100HCID 178512100, compound

Product 1

HCID 178476576HCID 178476576, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 25.0 g. of 1-benzyl-3-(2,6-dichlorobenzylideneamino)guanidine and 15 ml. of glacial acetic acid in 100 ml. of absolute ethanol is heated briefly to solution and then diluted with 800 ml. of a 1:1 mixture of diethyl ether-petroleum ether (b.p. 35°-60° C.). On standing, crystallization occurs. The desired product is recovered by filtration as colorless crystals, m.p. 114°-119° C.

Workup

  1. additionA mixture of 25.0 g
  2. additiondiluted with 800 ml
  3. customcrystallization
  4. filtrationThe desired product is recovered by filtration as colorless crystals, m.p. 114°-119° C.

Sources & evidence

ORD record
ord-3f35be7f32c84ebeadec47f830de1ccb
Source dataset
uspto-grants-1978_08
Patent number
US04107326

Reaction notes

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