Methyl iodide → Pseudourea, 1,3-dibenzyl-2-methyl-2-thio-, hydriodide

HRID 2419787Notes

Reaction equation

HRID 2419787 reaction equation
[CH2:1]([NH:8][C:9]([NH:11][CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[S:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:19][I:20]>C(O)C>[IH:20].[CH2:1]([NH:8][C:9](=[N:11][CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[S:10][CH3:19])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 838375N,N'-Dibenzylthiourea

Product 1

HCID 203825Pseudourea, 1,3-dibenzyl-2-methyl-2-thio-, hydriodide

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 25.6 g. of 1,3-dibenzylthiourea and 10 ml. of methyl iodide in 500 ml. of absolute ethanol is heated at reflux for 16 hours to give a solution of the desired product.

Workup

  1. temperatureat reflux for 16 hours

Sources & evidence

ORD record
ord-63741f1cb2024c0593dd7d57974acf38
Source dataset
uspto-grants-1978_08
Patent number
US04107326

Reaction notes

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