HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Trifluoromethyl)aniline → 2'-Trifluoromethylbenzanilide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Trifluoromethyl)aniline | HCID 6922 | — |
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 2'-Trifluoromethylbenzanilide | HCID 137262 | 62.5% |
Reaction Steps
Using the procedure of Step A of Example 6, 40.28 g of o-trifluoromethyl aniline and 35.14 g of benzoyl chloride were reacted in the presence of 25.3 g of triethylamine in 400 ml of acetone to obtain 41.45 g of N-(2-trifluoromethylphenyl)-benzamide melting at 146° C which was used as is for the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04107310 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-01181043086a44bebb0854eef7338873 |
| Source note | uspto-grants-1978_08 |