HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Chlorothiophenol → 3-[(4-Chlorophenyl)sulfanyl]propanenitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Chlorothiophenol | HCID 7815 | — |
| Reactant | 3-Chloropropionitrile | HCID 10963 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-[(4-Chlorophenyl)sulfanyl]propanenitrile | HCID 1808805 | — |
Reaction Steps
10 ml of β-chloropropionitrile (0.13 mol) are added, whilst stirring at 70°-80° C, to a solution of 17.4 g (0.12 mol) of p-chlorothiophenol and 4.8 g of sodium hydroxide pellets in 50 ml of water. The mixture is kept at 80° C for half an hour. After cooling, it is extracted with ether and the extract is washed with water and dried. 22.5 g of 3-(p-chlorophenylthio)-propionitrile. Melting point = 53-54° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04107438 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-e8fefa89b6a8448ba476d60f771b16df |
| Source note | uspto-grants-1978_08 |