Diazomethane → HCID 20314482, compound

HRID 2419916Notes

Reaction equation

HRID 2419916 reaction equation
[N+](=[CH2:3])=[N-].[Cl:4][C:5]1[CH:23]=[CH:22][C:8]([O:9][C:10]([C:18]([F:21])([F:20])[F:19])([C:14]([F:17])([F:16])[F:15])[C:11]([OH:13])=[O:12])=[CH:7][CH:6]=1>CCOCC>[Cl:4][C:5]1[CH:6]=[CH:7][C:8]([O:9][C:10]([C:14]([F:17])([F:16])[F:15])([C:18]([F:19])([F:20])[F:21])[C:11]([O:13][CH3:3])=[O:12])=[CH:22][CH:23]=1

Participants

4

Reactant 2

HCID 9550DiazomethaneHCID 133842322-(4-Chlorophenoxy)-3,3,3-trifluoro-2-(trifluoromethyl)propanoic acid

Product 1

HCID 20314482HCID 20314482, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

An excess of a solution of diazomethane in ether is added to an ethereal solution of 2-(4-chlorophenoxy)-3,3,3-trifluoro-2-trifluoromethylpropionic acid (0.25 g.) at 0° C. Evaporation of the resulting solution yields methyl 2-(4-chlorophenoxy)-3,3,3-trifluoro-2-trifluoromethylpropionate (0.25 g.), b.p. (bath temperature) 140° C. at 30 mm. pressure.

Workup

  1. customEvaporation of the resulting solution

Sources & evidence

ORD record
ord-03ae3cc504ab4ecfb56eac0d7b916ca2
Source dataset
uspto-grants-1978_08
Patent number
US04107329

Reaction notes

Loading…