Diazomethane → HCID 13384290, compound

HRID 2419932Notes

Reaction equation

HRID 2419932 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([CH2:13][O:14][C:15]([CH3:23])([C:19]([F:22])([F:21])[F:20])[C:16]([OH:18])=[O:17])[CH:7]=[CH:6]2.[N+](=[CH2:26])=[N-]>CCOCC>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([CH2:13][O:14][C:15]([CH3:23])([C:19]([F:20])([F:21])[F:22])[C:16]([O:18][CH3:26])=[O:17])[CH:7]=[CH:6]2

Participants

4

Reactant 2

HCID 9550DiazomethaneHCID 13384291HCID 13384291, compound

Product 1

HCID 13384290HCID 13384290, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A solution of (±)-2-(6-methoxy-2-naphthylmethoxy)-3,3,3-trifluoro-2-methylpropionic acid (1.0 g.) in ether is treated with diazomethane by the process described in Example 18 to give (±)-methyl 2-(6-methoxy-2-naphthylmethoxy)-3,3,3-trifluoro-2-methylpropionate (0.8 g.) m.p. 60°-62° C. (from methanol at -50° C.).

Sources & evidence

ORD record
ord-6aaeb9fcb53f4c4cb5f8517eed7468c0
Source dataset
uspto-grants-1978_08
Patent number
US04107329

Reaction notes

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