Diazomethane → HCID 13384247, compound

HRID 2419933Notes

Reaction equation

HRID 2419933 reaction equation
[O:1]([C:8]1[CH:23]=[CH:22][C:11]([O:12][C:13]([CH3:21])([C:17]([F:20])([F:19])[F:18])[C:14]([OH:16])=[O:15])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N+](=[CH2:26])=[N-]>CCOCC>[O:1]([C:8]1[CH:23]=[CH:22][C:11]([O:12][C:13]([CH3:21])([C:17]([F:18])([F:19])[F:20])[C:14]([O:16][CH3:26])=[O:15])=[CH:10][CH:9]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 9550DiazomethaneHCID 133842483,3,3-Trifluoro-2-methyl-2-(4-phenoxyphenoxy)propanoic acid

Product 1

HCID 13384247HCID 13384247, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A solution of (±)-2-(4-phenoxyphenoxy)-3,3,3-trifluoro-2-methylpropionic acid (6.4 g.) in ether is treated with an excess of ethereal diazomethane at 0° C. The solution is evaporated and the residue distilled to give (±)-methyl 2-(4-phenoxyphenoxy)-3,3,3-trifluoro-2-methylpropionate (3.3 g.), b.p. 187° C. at 0.1 mm. pressure.

Workup

  1. customThe solution is evaporated
  2. distillationthe residue distilled

Sources & evidence

ORD record
ord-a46320baddb04f0088a833530f1cfb73
Source dataset
uspto-grants-1978_08
Patent number
US04107329

Reaction notes

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