HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxybenzylamine → 4-Chloromethyl-N-(3-methoxybenzyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxybenzylamine | HCID 21156 | — |
| Reactant | 4-(Chloromethyl)benzoyl chloride | HCID 70136 | — |
| Product | 4-Chloromethyl-N-(3-methoxybenzyl)benzamide | HCID 19690086 | 83.9% |
Reaction Steps
Using 3-methoxybenzylamine (754 mg, 5.39 mmol) and 4-chloromethylbenzoyl chloride (1.17 g, 6.0 mmol), the procedure of Reference Example 13 was repeated to obtain 1.31 g (83.9%) of the title compound in the form of colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05728835 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-fc00450aae7f43bba3081ae919487779 |
| Source note | uspto-grants-1998_03 |