Sodium hydride → HCID 53894239, compound

Participants

Reaction Steps

3.86 g of 1B, 5.2 g of 3-phenoxybenzyl bromide and 30 ml of tetrahydrofuran were mixed and 0.9 g of sodium hydride was added. The mixture was heated to 35°. The mixture was cooled, stirred at room temperature for 21 hours, then filtered, and the solvent was stripped from the filtrate. The liquid residue was chromatographed (silica gel, 1/2 v/v methylene chloride/pentane) to give (1C), 1-(4-chlorophenyl)-2-methyl-1-propanone O-((3-phenoxyphenyl)methyl)oxime as a light yellow liquid, boiling point not determined.

Provenance & Evidence