HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(Bicyclo[3.2.1]oct-2-ylidene)pentanoic acid → 5-(Bicyclo[3.2.1]oct-2-yl)pentanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(Bicyclo[3.2.1]oct-2-ylidene)pentanoic acid | HCID 53878493 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-(Bicyclo[3.2.1]oct-2-yl)pentanoic acid | HCID 21325432 | — |
Reaction Steps
A solution of 3.4 g (16.3 mmol) of 5-(bicyclo[3.2.1]oct-2-ylidene)pentanoic acid in 100 ml of absolute ethanol was hydrogenated at 50 psi over 300 mg of platinum oxide in a Parr apparatus. After 1.5 hr hydrogen uptake became slow. After 4 hr the system was flushed with nitrogen, and the catalyst was removed by filtration through diatomaceous earth filter aid (Celite). The filtrate was evaporated in vacuo to yield 3.25 g (96%) of quite pure 5-(bicyclo[3.2.1]oct-2-yl)pentanoic acid as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04108892 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-1fb64ff6579f4ef08f09dbd8ae9d9ea6 |
| Source note | uspto-grants-1978_08 |