反应详情

19.0 grams (g) of 3,5-dimethyl-4-aminopyrazole hydrochloride and 19.7 g of ammonium thiocyanate are dissolved in 100 milliliters (ml) of water, and the resulting solution is heated at boiling under reflux for 6 hours. Then the solution is concentrated to about 50 ml and cooled. Thus-formed precipitate is separated by filtration, washed with a little water and dried to yield 17.0 g of 3,5-dimethyl-4-thioureidopyrazole, mp 209° to 211°.

1. temperaturethe resulting solution is heated
2. temperatureunder reflux for 6 hours
3. concentrationThen the solution is concentrated to about 50 ml
4. temperaturecooled
5. customThus-formed precipitate
6. customis separated by filtration
7. washwashed with a little water
8. customdried