HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 20313019, compound → HCID 20313018, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 20313019 | HCID 20313019 | — |
| Solvent | Hydrogen Bromide | HCID 260 | — |
| Product | HCID 20313018 | HCID 20313018 | 59.4% |
Reaction Steps
Twenty milliliters of 48% hydrobromic acid were added to 1.5 g of 5-(3,4-dimethoxybenzyl)picolinic acid. The mixture was heated under reflux for 6 hours. After allowing to cool, crystals formed were collected by filtration. The crystals were dissolved in 10% aqueous ammonia, treated with active carbon and adjusted to pH 2-3 with dilute hydrochloric acid to form crystals. The crystals were collected by filtration to obtain 0.8 g of 5-(3,4-dihydroxybenzyl)picolinic acid as reddish brown crystals of a decomposition point of 246°~249° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04109000 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-ad5869dd51c5458d9bb95329d053b6ec |
| Source note | uspto-grants-1978_08 |