HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 20313027, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | 2-Pyridinecarboxylic acid, 5-((4-hydroxyphenyl)methyl)- | HCID 3043792 | — |
| Product | HCID 20313027 | HCID 20313027 | — |
Reaction Steps
One gram of 5-(4-hydroxybenzyl)-picolinic acid was suspended in 15 ml. of methanol. Then, hydrogen chloride gas was introduced therein till saturation. After heating under reflux for 5 hours, the reaction mixture was concentrated under reduced pressure. The residue was added with cold water to form crystals. The crystals were then recrystallized from ethyl acetate to obtain 0.85 g of methyl 5-(4-hydroxybenzyl)picolinate as colorless needlelike crystals of a melting point of 184°~186° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04109000 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-30728150a8064cf6b3eeaead6362d332 |
| Source note | uspto-grants-1978_08 |