Morpholine → HCID 20313194, compound

HRID 2420155Notes

Reaction equation

C(O[C:4]([C:6]1[C:14](=[O:15])[N:13]2[C:9](=[N:10][C:11]3[CH:19]=[CH:18][CH:17]=[CH:16][C:12]=32)[N:8]([CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH:7]=1)=[O:5])C.[NH:27]1[CH2:32][CH2:31][O:30][CH2:29][CH2:28]1>>[CH2:20]([N:8]1[C:9]2=[N:10][C:11]3[CH:19]=[CH:18][CH:17]=[CH:16][C:12]=3[N:13]2[C:14](=[O:15])[C:6]([C:4]([N:27]2[CH2:32][CH2:31][O:30][CH2:29][CH2:28]2)=[O:5])=[CH:7]1)[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

Participants

Reactant 2

HCID 8083Morpholine

HCID 56626788HCID 56626788, compound

Product 1

HCID 20313194HCID 20313194, compound

Procedure

By substituting 1-benzyl-1,4-dihydro-4-oxo-pyrimido-[1,2-a]benzimidazole-3-carboxylic acid ethyl ester in part a and morpholine in part b of Example 33, 1-benzyl-3-(4-morpholinylcarbonyl)pyrimido[1,2-a]benzimidazol-4(1H)one is obtained.

Sources & evidence

ORD record: ord-c26c71acee1742beb74befb7ce3b5b4d
Source dataset: uspto-grants-1978_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04109091

Reaction notes

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