Nitric Acid → HCID 20311075, compound

HRID 2420201Notes

Reaction equation

HRID 2420201 reaction equation
[C:1]([NH:4][C:5]1[CH:10]=[C:9]([O:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[CH:8]=[CH:7][C:6]=1[O:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36])(=[O:3])[CH3:2].[N+:37]([O-])([OH:39])=[O:38]>C(O)(=O)C>[N+:37]([C:8]1[C:9]([O:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])=[CH:10][C:5]([NH:4][C:1](=[O:3])[CH3:2])=[C:6]([O:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36])[CH:7]=1)([O-:39])=[O:38]

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 20311077HCID 20311077, compound

Product 1

HCID 20311075HCID 20311075, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent2×

Procedure

The product of Stage 3 (22.8 g) is suspended in 250 ml of glacial acetic acid. 4.9 ml of nitric acid of density 1.39 are added dropwise with stirring at room temperature, the mixture becoming pasty. Following the addition of another 50 ml of glacial acetic acid, the mixture is stirred for a few hours and filtered under suction. The filtered residue is suspended twice with acetonitrile, filtered under suction and dried.

Workup

  1. stirringthe mixture is stirred for a few hours
  2. filtrationfiltered under suction
  3. filtrationfiltered under suction
  4. customdried

Sources & evidence

ORD record
ord-4b746e2f2f774ac499ce1ca2aca3d523
Source dataset
uspto-grants-1978_08
Patent number
US04110113

Reaction notes

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