HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Acetate → 5,7-Dichloro-2,6-dimethylbenzoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | N-(3,5-Dichloro-2-hydroxy-4-methylphenyl)acetamide | HCID 13796880 | — |
| Product | 5,7-Dichloro-2,6-dimethylbenzoxazole | HCID 14419019 | — |
Reaction Steps
A mixture of 79 g. of 2-acetylamino-5-methyl-4,6-di-chloro-phenol and 3.6 g. of anhydrous sodium acetate was heated at 180° C. for some minutes. The liquid obtained was distilled under vacuum, collecting the fraction passed from 140° C. to 145° C. at 1.2 mm. Hg. The distilled oil became a mass of crystals which was purified by crystallization from ligroin. 36 g. of pure base were obtained. M.P. = 80°-82° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04110116 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-40c5016a1f734a95816ab8afa5e77933 |
| Source note | uspto-grants-1978_08 |