Sodium Hydroxide → 2,2-Diphenylcyclopropylmethyl dimethylamine

Participants

Reaction Steps

To a solution of lithium aluminum hydride (0.30 g) in ether (10 ml) was added a solution of 2,2-diphenylcyclopropanecarboxylic acid N,N-dimethylamide (0.813 g) in ether (15 ml) under ice-cooling, and the resulting mixture was stirred under reflux for 2 hours. The reaction mixture was cooled, admixed with a 10% aqueous solution of sodium hydroxide (20 ml) and extracted with ether. The ether extract was dried over anhydrous magnesium sulfate and evaporated to afford N,N-dimethyl-2,2-diphenylcyclopropylmethylamine (0.701 g) as an oily substance. M.P. 231°-233° C (hydrochloride).

Provenance & Evidence