HCID 20335745, compound → HCID 20335730, compound

Participants

Reaction Steps

33 grams of 1-keto-6-phenyl-8-chloro-1,2-dihydro-4H-s-triazolo-(4,3-a)-pyrido-(2,3-f)-(1,4)-diazepine-5-oxide were hydrogenated with 15 grams of Raney-nickel in 450 ml. of dimethyl formamide at 50 atmospheres absolute and 60°-70° C. After filtering off the catalyst with suction, the solution was concentrated to 100 ml., and then treated with water up to turbidity, whereupon the reaction product crystallized out. It was recrystallized from ethanol several times. Yield 15 grams; M.P. 222°-224° C.

Provenance & Evidence