HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylaminopropyl chloride, hydrochloride → HCID 20312118, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylaminopropyl chloride, hydrochloride | HCID 145749 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | HCID 13653425 | HCID 13653425 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 20312118 | HCID 20312118 | — |
Reaction Steps
3-Diethylaminopropyl chloride hydrochloride (3.75 g, 0.024 mole) and a solution of 5-(5-methoxyindol-3-ylmethyl)hydantoin (6.1 g, 0.024 mole) in 100 ml of DMF were added to a solution of sodium (1.1 g) in 200 ml of anhydrous ethanol and the mixture was heated to reflux with stirring for 8 hours, filtered and concentrated in vacuo. The residue was recrystallized from aqueous methanol, yield 1.8 g, mp 136°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04110536 |
| Source dataset | uspto-grants-1978_08 |
| ORD ID | ord-5cc302f6ec124247b4410e4dff2eb9ae |
| Source note | uspto-grants-1978_08 |