Benzylamine → HCID 58246226, compound

Participants

Reaction Conditions

Reaction Steps

6-Chloro-N-(2-(1-(1-(4-chlorophenyl)cyclobutyl)-3,4-dihydroisoquinolin-7-yloxy)ethyl)pyridine-3-sulfonamide (70.0 mg, 0.132 mmol) and benzylamine (14.2 mg, 0.133 mmol) were dissolved in dry ethanol (3 ml) and stirred in a microwave oven at 150° C. for 1 h. The solvent was reduced under vacuo and the residue was purified by column chromatography using silica gel and heptan/ethyl acetate (3:7->7:3) as the eluent. The product was obtained as a white solid (79 mg, 0.132 mmol, 20%).

Provenance & Evidence