HCID 86735979, compound → HCID 70595812, compound

HRID 2420596Notes

Reaction equation

HRID 2420596 reaction equation
[C:1]1([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH:7]([CH3:12])[CH2:8][CH:9]=[N:10]O>C(O)(=O)C.[Zn]>[C:1]1([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH:7]([CH3:12])[CH2:8][CH2:9][NH2:10]

Participants

4

Reactant 1

HCID 86735979HCID 86735979, compound

Product 1

HCID 70595812HCID 70595812, compound

Reagents, catalysts & solvents 2

HCID 23994ZincCatalystHCID 176Acetic AcidSolvent

Procedure

1.5 g of zinc dust are added, while stirring, to a solution of 2.39 g of 3-p-biphenylyl-butanaldoxime in 25 ml of acetic acid. The mixture is stirred for a further 4 hours, filtered, diluted with water, rendered alkaline with ammonia and extracted with chloroform. After the customary working up, 3-p-biphenylyl-butylamine is obtained. Hydrochloride, m.p. 226°-228°.

Workup

  1. filtrationfiltered
  2. additiondiluted with water
  3. extractionextracted with chloroform

Sources & evidence

ORD record
ord-f19200a9d33b4c4598dbd41a7a0fcfb9
Source dataset
uspto-grants-1978_08
Patent number
US04110447

Reaction notes

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