Imidazole → HCID 70597479, compound

HRID 2420608Notes

Reaction equation

HRID 2420608 reaction equation
Cl[CH2:2][CH2:3][C:4]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)([OH:6])[CH3:5].[NH:19]1[CH:23]=[CH:22][N:21]=[CH:20]1>>[N:19]1([CH2:2][CH2:3][C:4]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)([OH:6])[CH3:5])[CH:23]=[CH:22][N:21]=[CH:20]1

Participants

3

Reactant 2

HCID 795ImidazoleHCID 70595719HCID 70595719, compound

Product 1

HCID 70597479HCID 70597479, compound

Procedure

A mixture of 2.6 g of 1-chloro-3-p-biphenylyl-butan-3-ol and 1.36 g of imidazole is heated at 140° for 3 hours. After cooling and working up in the customary manner, 1-(1-imidazolyl)-3-p-biphenylyl-butan-3-ol is obtained.

Workup

  1. temperatureis heated at 140° for 3 hours
  2. temperatureAfter cooling

Sources & evidence

ORD record
ord-31ecb47336ba459697c939f02aa76a43
Source dataset
uspto-grants-1978_08
Patent number
US04110447

Reaction notes

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