Acetic Anhydride → HCID 86735982, compound

HRID 2420620Notes

Reaction equation

HRID 2420620 reaction equation
[C:1]1([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH:7]([CH3:11])[CH2:8][CH2:9][NH2:10].[C:18](OC(=O)C)(=[O:20])C>C(O)=O>[CH:18]([NH:10][CH2:9][CH2:8][CH:7]([C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][C:1]=1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH3:11])=[O:20]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 70595812HCID 70595812, compound

Product 1

HCID 86735982HCID 86735982, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

2.25 g of 3-p-biphenylyl-butylamine are dissolved in 30 ml of formic acid, 10 ml of acetic anhydride are added dropwise at 60°, while stirring, and the mixture is allowed to stand overnight and worked up in the customary manner to give 1-formamido-3-p-biphenylyl-butane.

Sources & evidence

ORD record
ord-de954be2a3d54de5919bb3aea1c8e7ab
Source dataset
uspto-grants-1978_08
Patent number
US04110447

Reaction notes

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