HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → (6-Fluoro-3-pentylchroman-7-ylmethyl)triphenylphosphonium bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | 7-Bromomethyl-6-fluoro-3-pentylchroman | HCID 59288330 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | (6-Fluoro-3-pentylchroman-7-ylmethyl)triphenylphosphonium bromide | HCID 86641033 | — |
Reaction Steps
11.0 g (34.9 mmol) of 7-bromomethyl-6-fluoro-3-pentylchroman and 9.20 g (35.1 mmol) of triphenylphosphine are dissolved in 70 ml of acetonitrile, and the mixture is stirred overnight at room temp. The batch is subsequently cooled to 0° C., and the precipitated (6-fluoro-3-pentylchroman-7-ylmethyl)triphenylphosphonium bromide is filtered off with suction and dried in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07955664B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-6d632f961daf4b1d887ac4b6a7a21d85 |
| Source note | uspto-grants-2011_06 |