HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Chlorophenyl)-1H-pyrrole-2-carboxylic acid → N-(3-chloro-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-4-(4-chlorophenyl)-1H-pyrrole-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Chlorophenyl)-1H-pyrrole-2-carboxylic acid | HCID 12897099 | — |
| Reactant | 3-Chloro-4-[2-(pyrrolidin-1-yl)ethoxy]aniline | HCID 19626995 | — |
| Product | N-(3-chloro-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-4-(4-chlorophenyl)-1H-pyrrole-2-carboxamide | HCID 67215310 | — |
Reaction Steps
3-Chloro-4-(2-(pyrrolidin-1-yl)ethoxy)benzenamine was converted to the title compound (20 mg) by acylation with 4-(4-chlorophenyl)-1H-pyrrole-2-carboxylic acid following the procedure described in step C of Example 1. MS (ESI) 444 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07956049B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-1095ba4d631141fdbbad0c9c69f54e05 |
| Source note | uspto-grants-2011_06 |