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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2420716Generated: November 2, 2026

4-(4-Chlorophenyl)-1H-pyrrole-2-carboxylic acid → HCID 67215196, compound

https://huagongshe.com/reaction/2420716

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Chlorophenyl)-1H-pyrrole-2-carboxylic acidHCID 12897099—
Reactant(3R)-1-(4-Amino-2-methoxyphenyl)pyrrolidin-3-olHCID 67215346—
ProductHCID 67215196HCID 67215196—

Reaction Steps

(R)-1-(4-Amino-2-methoxyphenyl)pyrrolidin-3-ol, preparation described in PCT application WO 2005/042541, was converted to the title compound (48 mg) by acylation with 4-(4-chlorophenyl)-1H-pyrrole-2-carboxylic acid (30 mg) following the procedure described in step C of Example 1. MS (ESI) 412 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07956049B2
Source datasetuspto-grants-2011_06
ORD IDord-4aa10a2d16344848a5f47bef1e98ae62
Source noteuspto-grants-2011_06