2-Methoxy-4-nitrophenol → HCID 67215421, compound
Reaction equation
[K].[CH3:2][O:3][C:4]1[CH:9]=[C:8]([N+:10]([O-])=O)[CH:7]=[CH:6][C:5]=1[OH:13].Br[CH2:15][CH2:16][N:17]1[CH:21]=[CH:20][CH:19]=[CH:18]1>>[N:17]1([CH2:16][CH2:15][O:13][C:5]2[CH:6]=[CH:7][C:8]([NH2:10])=[CH:9][C:4]=2[O:3][CH3:2])[CH:21]=[CH:20][CH:19]=[CH:18]1Participants
4
Procedure
Following procedure described in step A of Example 18, the title compound was prepared from the potassium salt of 2-methoxy-4-nitrophenol and 1-(2-bromoethyl)-1H-pyrrole in 76% yield. MS (ESI) 233 (M+H)+.
Sources & evidence
- ORD record
- ord-66886c53d42c48a2a2ef5c8a72e6392e
- Source dataset
- uspto-grants-2011_06
- Patent number
- US07956049B2
Reaction notes
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