1,2-Dibromoethane → HCID 24772294, compound

HRID 2420723Notes

Reaction equation

HRID 2420723 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]([C:13]([NH:15][C:16]3[CH:21]=[CH:20][C:19]([O:22][CH2:23][CH2:24][C:25]([OH:28])([CH3:27])[CH3:26])=[C:18]([O:29][CH3:30])[CH:17]=3)=[O:14])[NH:11][CH:12]=2)=[CH:4][CH:3]=1.Br[CH2:32][CH2:33]Br>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:9]=[C:10]3[C:13](=[O:14])[N:15]([C:16]4[CH:21]=[CH:20][C:19]([O:22][CH2:23][CH2:24][C:25]([OH:28])([CH3:27])[CH3:26])=[C:18]([O:29][CH3:30])[CH:17]=4)[CH2:33][CH2:32][N:11]3[CH:12]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 78391,2-DibromoethaneHCID 67214733HCID 67214733, compound

Product 1

HCID 24772294HCID 24772294, compound

Procedure

Following the procedure described in Example 1 step D, the product of step B (120 mg) was alkylated with 1,2-dibromoethane to yield 15 mg of the title compound. MS (ESI) 455 (M+H)+.

Sources & evidence

ORD record
ord-9986c36b5c6d492998f1591fbb56f91a
Source dataset
uspto-grants-2011_06
Patent number
US07956049B2

Reaction notes

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