HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Benzyloxy-phenyl)-ethylamine → N-{2-[4-(Benzyloxy)phenyl]ethyl}-1-(4-chloro-2-methoxyphenyl)cyclobutanecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Benzyloxy-phenyl)-ethylamine | HCID 200957 | — |
| Reactant | 1-(4-Chloro-2-methoxyphenyl)cyclobutane-1-carboxylic acid | HCID 58246291 | — |
| Product | N-{2-[4-(Benzyloxy)phenyl]ethyl}-1-(4-chloro-2-methoxyphenyl)cyclobutanecarboxamide | HCID 66868466 | — |
Reaction Steps
N-{2-[4-(Benzyloxy)phenyl]ethyl}-1-(4-chloro-2-methoxyphenyl)cyclobutanecarboxamide was prepared analogously to example 65 from 1-(4-chloro-2-methoxyphenyl)cyclobutanecarboxylic acid (3.45 g, 14.3 mmol) and 2-[4-(benzyloxy)phenyl]ethanamine (4.2 g, 15.92 mmol). Yield: 4.7 g (10.45 mmol, 66%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08653100B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-73452d70dd92436ab6b30dd7de6e0c2e |
| Source note | uspto-grants-2014_02 |