HCID 14722178, compound → HCID 10039959, compound

HRID 2420781Notes

Reaction equation

HRID 2420781 reaction equation
C([O:3][C:4](=[O:24])[C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([NH:11][C:12]2[N:17]=[C:16]([C:18]3[CH:19]=[N:20][CH:21]=[CH:22][CH:23]=3)[CH:15]=[CH:14][N:13]=2)[CH:6]=1)C.C(OC(=O)C1C=CC(C)=C(NC2N=C(C3C=NC=CC=3)C=CN=2)C=1)C>>[N:20]1[CH:21]=[CH:22][CH:23]=[C:18]([C:16]2[CH:15]=[CH:14][N:13]=[C:12]([NH:11][C:7]3[CH:6]=[C:5]([CH:10]=[CH:9][CH:8]=3)[C:4]([OH:24])=[O:3])[N:17]=2)[CH:19]=1

Participants

3

Reactant 2

HCID 14722178HCID 14722178, compoundHCID 44828737Ethyl 4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzoate

Product 1

HCID 10039959HCID 10039959, compound

Procedure

Utilising the procedure described in example 1c but employing 3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-benzoic acid ethyl ester in lieu of 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-benzoic acid ethyl ester, afforded the title compound as a crystalline solid, m.p. 291-295° C.

Sources & evidence

ORD record
ord-f86fb441bc434f04a51c54582d22b1dd
Source dataset
uspto-grants-2011_06
Patent number
US07956053B2

Reaction notes

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