2,4-Dichlorobenzylidenemalononitrile → 7-Amino-5-(2,4-dichlorophenyl)-2-(methylthio)[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitrile

HRID 2420789Notes

Reaction equation

HRID 2420789 reaction equation
[CH3:1][S:2][C:3]1[NH:7][N:6]=[C:5]([NH2:8])[N:4]=1.[Cl:9][C:10]1[CH:21]=[C:20]([Cl:22])[CH:19]=[CH:18][C:11]=1[CH:12]=[C:13]([C:16]#[N:17])[C:14]#[N:15]>>[NH2:17][C:16]1[N:6]2[N:7]=[C:3]([S:2][CH3:1])[N:4]=[C:5]2[N:8]=[C:12]([C:11]2[CH:18]=[CH:19][C:20]([Cl:22])=[CH:21][C:10]=2[Cl:9])[C:13]=1[C:14]#[N:15]

Participants

3

Reactant 2

HCID 180892,4-Dichlorobenzylidenemalononitrile2×HCID 178503514HCID 178503514, compound

Product 1

HCID 672140907-Amino-5-(2,4-dichlorophenyl)-2-(methylthio)[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitrile

Procedure

According to the procedure of Example 1, Step A, commercial 5-(methylthio)-1H-1,2,4-triazol-3-amine and (2,4-dichlorobenzylidene)malononitrile (Intermediate 1) were reacted to give the title compound as a dark brown solid. LC-MS 351 (M+1).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-5aeee39d20024fdfbcf9145f243cbb9c
Source dataset
uspto-grants-2011_06
Patent number
US07956061B2

Reaction notes

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