Trifluoroacetic acid → HCID 11226087, compound

Participants

Reaction Steps

tert-Butyl 2-chloro-5-[({(2R)-3-[4-(3,4-dichloro-2-methylphenoxy)piperidin-1-yl]-2-hydroxypropyl}amino)carbonyl]benzoate (0.14 g) in DCM (5 mL) was treated with trifluoroacetic acid (1.5 mL) and the mixture was stirred for 1.5 h. The solvent was evaporated. The product was purified by RPHPLC (Symmetry, 0.1% ammonium acetate/acetonitrile) to yield the title compound as a white solid. (0.05g).

Provenance & Evidence