HCID 24883329, compound → HCID 59025410, compound

Participants

Reaction Steps

To a solution of benzyl 4-[(3aR,7aR)-2-oxooctahydro-1H-benzimidazol-1-yl]-1,4′-bipiperidine-1′-carboxylate-(880 mg, 2.0 mmol) in methanol (25 mL) was added 10% Pd/C (0.1 g), the mixture was hydrogenated at 40 psi for 12 h. Filtration of catalyst and concentration of solvents afforded crude product (600 mg, 98%), which was used for the next step without further purification. MS (M+1): 307.31

Provenance & Evidence