HCID 86653007, compound → HCID 66869174, compound

Participants

Reaction Steps

N-[2-({1-[1-(6-Chloropyridin-2-yl)cyclobutyl]-1,2,3,4-tetrahydroisoquinolin-7-yl}oxy)ethyl]propane-1-sulfonamide (9 mg) were dissolved in methanol (1 ml). 10% Palladium on charcoal (5 mg) was added and the reaction mixture was stirred under an atmosphere of hydrogen at room temperature for 36 hours. The catalyst was removed by filtration and washed with methanol. The solvent was evaporated in vacuo. 5N isopropanolic hydrochloric acid (0.5 ml) was added. The solvent was evaporated in vacuo. Yield: 9 mg.

Provenance & Evidence