HCID 11550473, compound → (1R,2S)-N1-(tert-Butoxycarbonyl)-1,2-cyclohexanediamine

Participants

Reaction Steps

To a solution of compound (1R,2S) (2-Azidocyclohexyl-carbamic acid) tert-butyl ester (1.8 g, 7.5 mmol) in methanol (20 mL), 10% Pd—C (360 mg) was added and hydrogenated at 32 psi for 4 h Parr hydrogenator. The reaction mixture was filtered on a celite pad and the filterate was concentrated to give the title compound as a solid (1.1 g, 69%), which was used without further purification. MS: (M+1): 215.07

Provenance & Evidence