HCID 59025439, compound → HCID 24883077, compound

Participants

Reaction Steps

To a solution of cis-(+/−)-benzyl-4-(2-oxooctahydro-1H-benzimidazol-1-yl)-1,4′-bipiperidine-1′-carboxylate (800 mg, 1.82 mmol) in EtOH (50 mL) was added 10% Pd/C (80 mg) and the mixture was hydrogenated at 40 psi for 3 h. Filtration of catalyst on celite and removal of solvent afforded the title compound (372 mg, 67%), which was used without further purification. MS (M+1): 306.0

Provenance & Evidence