HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Quinolinecarboxylic acid → HCID 67215164, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Quinolinecarboxylic acid | HCID 10243 | — |
| Reactant | 5-Methyl-3-phenyl-4-isoxazolecarbohydrazide | HCID 727924 | — |
| Product | HCID 67215164 | HCID 67215164 | 23% |
Reaction Steps
As described for example 2, 5-methyl-3-phenyl-isoxazole-4-carboxylic acid hydrazide (200 mg, 0.92 mmol) was converted using quinoline-4-carboxylic acid instead of o-toluic acid to the title compound (SiO2, heptane:ethyl acetate:dichloromethane=50:30:20 to 20:60:20, 75 mg, 23%) which was obtained as a white solid. MS: m/e=355.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07956074B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-4d12bc387827426498cc893807f53b3d |
| Source note | uspto-grants-2011_06 |