HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Iodobenzoic acid → HCID 67215624, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Iodobenzoic acid | HCID 12085 | — |
| Reactant | 5-Methyl-3-phenyl-4-isoxazolecarbohydrazide | HCID 727924 | — |
| Product | HCID 67215624 | HCID 67215624 | 62% |
Reaction Steps
As described for example 2, 5-methyl-3-phenyl-isoxazole-4-carboxylic acid hydrazide (1.00 g, 4.60 mmol) was converted using 4-iodobenzoic acid instead of o-toluic acid to the title compound (SiO2, heptane:ethyl acetate:dichloromethane=70:10:20 to 40:40:20, 1.21 g, 62%) which was obtained as a white solid. MS: m/e=430.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07956074B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-1d726351747d41529c2d277ce974dd94 |
| Source note | uspto-grants-2011_06 |