HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromopyridine-2-carboxylic acid → HCID 67215572, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromopyridine-2-carboxylic acid | HCID 608544 | — |
| Reactant | 5-Methyl-3-phenyl-4-isoxazolecarbohydrazide | HCID 727924 | — |
| Product | HCID 67215572 | HCID 67215572 | 39% |
Reaction Steps
As described for example 137a, 5-methyl-3-phenyl-isoxazole-4-carboxylic acid hydrazide (4.14 g, 19.0 mmol) using 5-bromo-2-carboxy pyridine instead of 6-chloronicotinic acid was converted to the title compound (2.83 g, 39%) which was obtained as a brown solid. MS: m/e=385.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07956074B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-2bfdafc5499b445b93cafac142292858 |
| Source note | uspto-grants-2011_06 |