HCID 59627921, compound → HCID 44193185, compound

Participants

Reaction Steps

A solution of 2-fluoro-4-{3-methyl-4-[(phenylmethyl)oxy]-1H-indol-1-yl}phenol (D2) (140 mg, 0.40 mmol) in ethanol (20 mL) was hydrogenated in an H-cube over a 10% Pd/C catalyst. The resulting solution was concentrated and the product purified by silica gel chromatography eluting with 5-50% ethyl acetate in hexane to yield the title compound (E2) (47 mg).

Provenance & Evidence