HCID 59627919, compound → HCID 44193186, compound

Participants

Reaction Steps

To a solution of 2-fluoro-4-{2-methyl-4-[(phenylmethyl)oxy]-1H-indol-1-yl}phenol (D3) (85 mg, 0.24 mmol) in ethanol (7 mL) was added a solution of tetra-n-butylammonium chloride (170 mg, 0.61 mmol) in ethyl acetate (1 mL). The solution was hydrogenated in an H-cube over a 10% Pd/C catalyst. The resulting solution was concentrated and the product purified by MDAP to yield the title compound (E3) (31 mg).

Provenance & Evidence