Cyclohexanone → HCID 178443966, compound

HRID 2421274Notes

Reaction equation

HRID 2421274 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:9]=[C:10]([CH:13]([NH2:20])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])[NH:11][CH:12]=2)=[CH:4][CH:3]=1.[C:21]1(=O)[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[N:9]=[C:10]([CH:13]([NH:20][CH:21]3[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]3)[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])[NH:11][CH:12]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 7967CyclohexanoneHCID 178443969HCID 178443969, compound

Product 1

HCID 178443966HCID 178443966, compoundYield 15%

Procedure

This compound is obtained according to an operating method similar to that of Stage 35.3 of Example 35 using as starting amine, 1-[4-(4-fluorophenyl)-1H-imidazol-2-yl]-1-heptanamine (0.5 g; 0.0014 mol) and as ketone, cyclohexanone (0.17 ml; 0.0014 mol). A white-coloured powder is obtained with a yield of 15%.

Workup

  1. customThis compound is obtained
  2. customA white-coloured powder is obtained with a yield of 15%

Sources & evidence

ORD record
ord-734a8664ae874b4490f96a46026db11f
Source dataset
uspto-grants-2011_06
Patent number
US07956075B2

Reaction notes

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