Acetyl chloride → HCID 10272950, compound

HRID 2421296Notes

Reaction equation

HRID 2421296 reaction equation
Cl.[CH:2]1[C:15]2[NH:14][C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[S:7][C:6]=2[CH:5]=[CH:4][C:3]=1[C:16]1[N:17]=[C:18]([CH2:21][NH2:22])[S:19][CH:20]=1.[C:23](Cl)(=[O:29])[CH2:24][CH2:25][CH2:26][CH2:27][CH3:28].C(Cl)(=O)C>>[CH:2]1[C:15]2[NH:14][C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[S:7][C:6]=2[CH:5]=[CH:4][C:3]=1[C:16]1[N:17]=[C:18]([CH2:21][NH:22][C:23](=[O:29])[CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[S:19][CH:20]=1

Participants

4

Reactant 3

HCID 6367Acetyl chlorideHCID 67340Hexanoyl chlorideHCID 67213853HCID 67213853, compound

Product 1

HCID 10272950HCID 10272950, compoundYield 40.7%

Procedure

This compound is prepared according to a protocol identical to that described for Example 355, with the compound of Example 362 and hexanoyl chloride respectively replacing intermediate 355.2 and acetyl chloride in Stage 355.3. The expected product is obtained in the form of a brown solid with a yield of 40.7%. Melting point: 192.0-194.0° C.

Workup

  1. customThis compound is prepared

Sources & evidence

ORD record
ord-6082194341e943f5abe31b422b987f59
Source dataset
uspto-grants-2011_06
Patent number
US07956075B2

Reaction notes

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